【Detection principle】 This product is quantitatively detected by fluorescence immunochromatography. Rationale: The nitrocellulose membrane is marked with T and C lines, and the T line is coated with an antibody a that specifically recognizes cTnI. The binding pad is sprayed with another fluorescent nanomaterial-labeled antibody b that can specifically recognize cTnI, and the cTnI in the sample first binds to the nanomaterial-labeled antibody b to form a complex, and then upward chromatography, the complex binds to the T-line antibody a to form a sandwich structure, and when irradiated with excitation light, the nanomaterial emits a fluorescent signal, and the strength of the signal is positively correlated with the concentration of cTnI in the sample.
【Detection purpose】 Troponin is a complex of three proteins: troponin T (TnT), troponin C (TnC), and troponin I (TnI). TnI is only present in cardiac tissue and is one of the most sensitive and specific serum markers for cardiomyocyte injury.